HOYER, Denton: search on Z-Library

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1

An analysis of FDA-approved drugs for infectious disease: antibacterial agents

Kinch, Michael S., Patridge, Eric, Plummer, Mark, Hoyer, Denton

Journal:

Drug Discovery Today

Year:

2014

Language:

english

File:

PDF, 965 KB

english, 2014

2

Target selection for FDA-approved medicines

Kinch, Michael S., Hoyer, Denton, Patridge, Eric, Plummer, Mark

Journal:

Drug Discovery Today

Year:

2015

Language:

english

File:

PDF, 545 KB

english, 2015

3

Pyrrolocin A, a 3-Decalinoyltetramic Acid with Selective Biological Activity, Isolated from Amazonian Cultures of the Novel Endophyte Diaporthales sp. E6927E

Patridge, Eric V., Darnell, Alicia, Kucera, Kaury, Phillips, Gillian M., Bokesch, Heidi R., Gustafson, Kirk R., Spakowicz, Daniel J., Zhou, Linda, Hungerford, William M., Plummer, Mark, Hoyer, Denton,

Journal:

Natural Product Communications

Year:

2015

File:

PDF, 451 KB

2015

4

Pyrrolocin A, a 3-Decalinoyltetramic Acid with Selective Biological Activity, Isolated from Amazonian Cultures of the Novel Endophyte Diaporthales sp. E6927E

Patridge, Eric V., Darnell, Alicia, Kucera, Kaury, Phillips, Gillian M., Bokesch, Heidi R., Gustafson, Kirk R., Spakowicz, Daniel J., Zhou, Linda, Hungerford, William M., Plummer, Mark, Hoyer, Denton,

Journal:

Natural Product Communications

Year:

2015

Language:

english

File:

PDF, 451 KB

english, 2015

5

An analysis of FDA-approved drugs: natural products and their derivatives

Patridge, Eric, Gareiss, Peter, Kinch, Michael S., Hoyer, Denton

Journal:

Drug Discovery Today

Year:

2015

Language:

english

File:

PDF, 924 KB

english, 2015

6

Duale genetische Kodierung von Acetyllysin und nicht-hydrolysierbarem Thioacetyllysin mittels Flexizym

Xiong, Hai, Reynolds, Noah M., Fan, Chenguang, Englert, Markus, Hoyer, Denton, Miller, Scott J., Söll, Dieter

Journal:

Angewandte Chemie

Year:

2016

File:

PDF, 995 KB

2016

7

Dual Genetic Encoding of Acetyl-lysine and Non-deacetylatable Thioacetyl-lysine Mediated by Flexizyme

Xiong, Hai, Reynolds, Noah M., Fan, Chenguang, Englert, Markus, Hoyer, Denton, Miller, Scott J., Söll, Dieter

Journal:

Angewandte Chemie International Edition

Year:

2016

Language:

english

File:

PDF, 985 KB

english, 2016

8

A Î³-Lactam Siderophore Antibiotic Effective Against Multidrug-Resistant Gram-Negative Bacilli

Goldberg, Joel, Nguyen, Ha, Kumar, Vijay, Spencer, Elizabeth, Hoyer, Denton, Marshall, Emma, Cmolik, Anna, O'Shea, Margaret, Marshall, Steven, Hujer, Andrea, Hujer, Kristine, Rudin, Susan D., Domitrov

Journal:

Journal of Medicinal Chemistry

Year:

2020

File:

PDF, 934 KB

2020

9

Aspartyl .alpha.-((1-Phenyl-3-(trifluoromethyl)- pyrazol-5-yl)oxy)methyl Ketones as Interleukin-1.beta. Converting Enzyme Inhibitors. Significance of the P1 and P3 Amido Nitrogens for Enzyme-Peptide Inhibitor Binding

Dolle, Roland E., Singh, Jasbir, Rinker, James, Hoyer, Denton, Prasad, C. V. C., Graybill, Todd L., Salvino, Joseph M., Helaszek, Carla T., Miller, Robert E., Ator, Mark A.

Journal:

Journal of Medicinal Chemistry

Year:

1994

Language:

english

File:

PDF, 464 KB

english, 1994

10

High-throughput screening identifies compounds that protect RPE cells from physiological stressors present in AMD

Cai, Hui, Gong, Jie, Abriola, Laura, Hoyer, Denton, Stem Cell Array Team, NYSCF Global, Noggle, Scott, Paull, Daniel, Del Priore, Lucian V., Fields, Mark A.

Journal:

Experimental Eye Research

Year:

2019

File:

PDF, 1.55 MB

2019

11

Stereochemistry of the Ph3P-CCl4 mediated cyclization of carboxylic acids and 1,2-amino alcohols (Vorbruggen Method)

A.I. Meyers, Denton Hoyer

Journal:

Tetrahedron Letters

Year:

1985

Language:

english

File:

PDF, 180 KB

english, 1985

12

P1 Aspartate-Based Peptide .alpha.-((2,6-Dichlorobenzoyl)oxy)methyl Ketones as Potent Time-Dependent Inhibitors of Interleukin-1.beta.-Converting Enzyme

Dolle, Roland E., Hoyer, Denton, Prasad, C. V. C., Schmidt, Stanley J., Helaszek, Carla T., Miller, Robert E., Ator, Mark A.

Journal:

Journal of Medicinal Chemistry

Year:

1994

Language:

english

File:

PDF, 291 KB

english, 1994

13

An overview of FDA-approved new molecular entities: 1827–2013

Kinch, Michael S., Haynesworth, Austin, Kinch, Sarah L., Hoyer, Denton

Journal:

Drug Discovery Today

Year:

2014

Language:

english

File:

PDF, 695 KB

english, 2014

14

An analysis of original research contributions toward FDA-approved drugs

Patridge, Eric V., Gareiss, Peter C., Kinch, Michael S., Hoyer, Denton W.

Journal:

Drug Discovery Today

Year:

2015

Language:

english

File:

PDF, 903 KB

english, 2015

15

New strategy for selective protein cleavage

Hoyer, Denton, Cho, Ho, Schultz, Peter G.

Journal:

Journal of the American Chemical Society

Year:

1990

Language:

english

File:

PDF, 866 KB

english, 1990

16

698. In vitro Activity of a New Generation Oxopyrazole Antibiotic Against Multidrug-Resistant Gram-Negative Bacilli

Goldberg, Joel, Bethel, Christopher, Hujer, Andrea M, Hujer, Kristine, Marshall, Steven, Papp-Wallace, Krisztina M, Perez, Federico, Spencer, Elizabeth, Hoyer, Denton, Plummer, Mark, Bonomo, Robert A

Journal:

Open Forum Infectious Diseases

Year:

2019

File:

PDF, 658 KB

2019

17

Design and synthesis of potent thiol-based inhibitors of endothelin converting enzyme-1

Cynthia A Fink, Michael Moskal, Fariborz Firooznia, Denton Hoyer, David Symonsbergen, Dongchu Wei, Ying Qiao, Paula Savage, Michael E Beil, Angelo J Trapani, Arco Y Jeng

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2000

Language:

english

File:

PDF, 140 KB

english, 2000

18

3-chloro-4-carboxamido-6-arylpyridazines as a non-peptide class of interleukin-1β converting enzyme inhibitor

Roland E. Dolle, Denton Hoyer, James M. Rinker, Tina Morgan Ross, Stanley J. Schmidt, Carla T. Helaszek, Mark A. Ator

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1997

Language:

english

File:

PDF, 182 KB

english, 1997

19

Pyridazinodiazepines as a High-Affinity, P 2 −P 3 Peptidomimetic Class of Interleukin-1β-Converting Enzyme Inhibitor

Dolle, Roland E., Prasad, C. V. C., Prouty, Catherine P., Salvino, Joseph M., Awad, Mohamed M. A., Schmidt, Stanley J., Hoyer, Denton, Ross, Tina Morgan, Graybill, Todd L., Speier, Gary J., Uhl, Joann

Journal:

Journal of Medicinal Chemistry

Year:

1997

Language:

english

File:

PDF, 462 KB

english, 1997

20

An analysis of FDA-approved drugs for cardiovascular diseases

Kinch, Michael S., Surovtseva, Yulia, Hoyer, Denton

Journal:

Drug Discovery Today

Year:

2014

Language:

english

File:

PDF, 777 KB

english, 2014

21

Palladium-Catalyzed Cross-Coupling in the Synthesis of Pyridinyl Boxazomycin C Analogues

Richardson, Chris, Rewcastle, Gordon W., Hoyer, Denton, Denny, William A.

Journal:

Journal of Organic Chemistry

Year:

2005

Language:

english

File:

PDF, 87 KB

english, 2005

22

Structural and stereochemical requirements of time-dependent inactivators of the interleukin-1β converting enzyme

C.V.C. Prasad, Catherine P. Prouty, Denton Hoyer, Tina M. Ross, Joseph M. Salvino, Mohamad Awad, Todd L. Graybill, Stanley J. Schmidt, I. Kelly Osifo, Roland E. Dolle, Carla T. Helaszek, Robert E. Mil

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1995

Language:

english

File:

PDF, 222 KB

english, 1995

23

Asymmetric tandem addition to chiral 1- and 2-substituted naphthalenes. Application to the synthesis of (+)-phyltetralin

Meyers, Albert I., Roth, Gregory P., Hoyer, Denton., Barner, Bruce A., Laucher, Dominique.

Journal:

Journal of the American Chemical Society

Year:

1988

Language:

english

File:

PDF, 1.70 MB

english, 1988

24

A history of drug development in four acts

Kinch, Michael S., Hoyer, Denton

Journal:

Drug Discovery Today

Year:

2015

Language:

english

File:

PDF, 508 KB

english, 2015

25

Structure activity relationships of non-peptide bradykinin B2 receptor antagonists

Joseph M. Salvino, Peter R. Seoane, Brent D. Douty, Mohamed A. Awad, Denton Hoyer, Tina Morgan Ross, Roland E. Dolle, Wayne T. Houck, David M. Faunce, David G. Sawutz

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1995

Language:

english

File:

PDF, 290 KB

english, 1995

26

Potent and Selective Non-Peptidic Inhibitors of Endothelin-Converting Enzyme-1 with Sustained Duration of Action

De Lombaert, Stéphane, Blanchard, Louis, Stamford, Lisa B., Tan, Jenny, Wallace, Eli M., Satoh, Yoshitaka, Fitt, John, Hoyer, Denton, Simonsbergen, David, Moliterni, John

Journal:

Journal of Medicinal Chemistry

Year:

2000

Language:

english

File:

PDF, 299 KB

english, 2000

27

Borate promoted electrophilic additions of alkyl hypohalites

Gene E. Heasley, Michael Duke, Denton Hoyer, John Hunnicutt, Mason Lawrence, Martin J. Smolik, Victor L. Heasley, Dale F. Shellhamer

Journal:

Tetrahedron Letters

Year:

1982

Language:

english

File:

PDF, 249 KB

english, 1982

28

Ace inhibitors as a template for the design of bradykinin B2 receptor antagonists

Denton Hoyer, Mohamed M.A. Awad, Joseph M. Salvino, Peter R. Seoane, Roland E. Dolle, Wayne T. Houck, David G. Sawutz

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1995

Language:

english

File:

PDF, 207 KB

english, 1995

29

Asymmetric tandem additions to chiral 2-naphthyloxazolines. The synthesis of enantiomerically pure 1,2,2-trisubstituted- 1,2-dihydronaphthalenes

A.I. Meyers, Denton Hoyer

Journal:

Tetrahedron Letters

Year:

1984

Language:

english

File:

PDF, 194 KB

english, 1984

30

α-((Tetronoyl)oxy)- and α-((tetramoyl)oxy)methyl ketone inhibitors of the interleukin-1β converting enzyme (ICE)

Todd L. Graybill, Catherine P. Prouty, Gary J. Speier, Denton Hoyer, Roland E. Dolle, Carla T. Helaszek, Mark A. Ator, Joanne Uhl, Joost Strastes

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1997

Language:

english

File:

PDF, 386 KB

english, 1997

31

Potent non-peptidic dual inhibitors of endothelin-converting enzyme and neutral endopeptidase 24.11

Stéphane De Lombaert, Lisa B. Stamford, Louis Blanchard, Jenny Tan, Denton Hoyer, Clive G. Diefenbacher, Dongchu Wei, Eli M. Wallace, Michael A. Moskal, Paula Savage, Arco Y. Jeng

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1997

Language:

english

File:

PDF, 324 KB

english, 1997

32

CGS 34226, a thiol-based dual inhibitor of endothelin converting enzyme-1 and neutral endopeptidase 24.11

JENG, Y. Arco, SAVAGE, Paula, BEIL, Michael E., BRUSEO, Charles W., HOYER, Denton, FINK, Cynthia A., TRAPANI, Angelo J.

Journal:

Clinical Science

Year:

2002

Language:

english

File:

PDF, 99 KB

english, 2002

33

687. In vitro Activity of a New Generation Oxopyrazole Antibiotic Against Acinetobacter spp.

Goldberg, Joel, Bethel, Christopher, Hujer, Andrea M, Hujer, Kristine, Marshall, Steven, Papp-Wallace, Krisztina M, Perez, Federico, Spencer, Elizabeth, Hoyer, Denton, Plummer, Mark, Bonomo, Robert A

Journal:

Open Forum Infectious Diseases

Year:

2019

File:

PDF, 170 KB

2019

34

Effects of the ECE/NEP inhibitor CGS 34225 on the big ET-1-induced pressor response and plasma atrial natriuretic peptide concentration in conscious rats

TRAPANI, Angelo J., BEIL, Michael E., BRUSEO, Charles W., FINK, Cynthia A., HOYER, Denton, SAVAGE, Paula, JENG, Arco Y.

Journal:

Clinical Science

Year:

2002

Language:

english

File:

PDF, 100 KB

english, 2002

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